3PBE
Crystal structure of the mutant W207F of human secretory glutaminyl cyclase
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B | Glutaminyl-peptide cyclotransferase | polymer | 329 | 37518.4 | 2 | UniProt (Q16769) Pfam (PF04389) In PDB | Homo sapiens (human) | Glutaminyl cyclase, QC, Glutaminyl-tRNA cyclotransferase, Glutamyl cyclase, EC |
| 2 | A, B | ZINC ION | non-polymer | 65.4 | 2 | Chemie (ZN) | |||
| 3 | A, B | SULFATE ION | non-polymer | 96.1 | 2 | Chemie (SO4) | |||
| 4 | water | water | 18.0 | 507 | Chemie (HOH) |
Sequence modifications
A, B: 33 - 361 (UniProt: Q16769)
| PDB | External Database | Details |
|---|---|---|
| Phe 207 | Trp 207 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 75036.7 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 322.9 | |
| All* | Total formula weight | 75359.7 |
