3OXI
Design and Synthesis of Disubstituted Thiophene and Thiazole Based Inhibitors of JNK for the Treatment of Neurodegenerative Diseases
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Mitogen-activated protein kinase 10 | polymer | 362 | 41799.4 | 1 | UniProt (P53779) Pfam (PF00069) In PDB | Homo sapiens (human) | MAP kinase 10, MAPK 10, Stress-activated protein kinase JNK3, c-Jun N-terminal kinase 3, MAP kinase p49 3F12 |
| 2 | J | Mitogen-activated protein kinase 8 interacting protein 1 | polymer | 10 | 1188.4 | 1 | UniProt (Q6NUQ9) UniProt (by SIFTS) (Q9UQF2) In PDB | Homo sapiens (human) | |
| 3 | A | methyl 3-[(thiophen-2-ylacetyl)amino]thiophene-2-carboxylate | non-polymer | 281.4 | 1 | Chemie (SYY) | |||
| 4 | water | water | 18.0 | 84 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 42987.8 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 281.4 | |
| All* | Total formula weight | 43269.1 |
