3NSJ
The X-ray crystal structure of lymphocyte perforin
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | Perforin-1 | polymer | 540 | 60799.0 | 1 | UniProt (P10820) Pfam (PF01823) Pfam (PF00168) In PDB | Mus musculus (mouse) | P1, Lymphocyte pore-forming protein, Cytolysin |
2 | A | GLYCEROL | non-polymer | 92.1 | 3 | Chemie (GOL) | |||
3 | A | CALCIUM ION | non-polymer | 40.1 | 2 | Chemie (CA) | |||
4 | A | IODIDE ION | non-polymer | 126.9 | 4 | Chemie (IOD) | |||
5 | A | CHLORIDE ION | non-polymer | 35.5 | 2 | Chemie (CL) | |||
6 | A | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 1 | Chemie (NAG) | |||
7 | water | water | 18.0 | 279 | Chemie (HOH) |
Sequence modifications
A: 21 - 554 (UniProt: P10820)
PDB | External Database | Details |
---|---|---|
Glu 213 | Arg 213 | engineered mutation |
His 555 | - | expression tag |
His 556 | - | expression tag |
His 557 | - | expression tag |
His 558 | - | expression tag |
His 559 | - | expression tag |
His 560 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 1 |
Total formula weight | 60799.0 | |
Non-Polymers* | Number of molecules | 12 |
Total formula weight | 1156.2 | |
All* | Total formula weight | 61955.1 |