3LGZ
Crystal structure of dehydrosqualene synthase Y129A from S. aureus complexed with presqualene pyrophosphate
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | B | Dehydrosqualene synthase | polymer | 293 | 34695.4 | 1 | UniProt (A9JQL9) Pfam (PF00494) In PDB | Staphylococcus aureus | 4,4'-diapophytoene synthase, DAP synthase, Diapophytoene synthase |
| 2 | B | {(1R,2R,3R)-2-[(3E)-4,8-dimethylnona-3,7-dien-1-yl]-2-methyl-3-[(1E,5E)-2,6,10-trimethylundeca-1,5,9-trien-1-yl]cyclopropyl}methyl trihydrogen diphosphate | non-polymer | 586.7 | 1 | Chemie (PS7) | |||
| 3 | B | MAGNESIUM ION | non-polymer | 24.3 | 2 | Chemie (MG) | |||
| 4 | water | water | 18.0 | 68 | Chemie (HOH) |
Sequence modifications
B: 1 - 287 (UniProt: A9JQL9)
| PDB | External Database | Details |
|---|---|---|
| Ala -5 | - | expression tag |
| Ala -4 | - | expression tag |
| Ala -3 | - | expression tag |
| Ala -2 | - | expression tag |
| Ala -1 | - | expression tag |
| Ala 0 | - | expression tag |
| Ala 129 | Tyr 129 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 34695.4 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 635.3 | |
| All* | Total formula weight | 35330.7 |
