3KUL

Kinase domain of human ephrin type-A receptor 8 (EPHA8)

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	Ephrin type-A receptor 8	polymer	325	36698.6	1	UniProt (P29322) Pfam (PF14575) Pfam (PF07714) In PDB	Homo sapiens (human)	Tyrosine-protein kinase receptor EEK, EPH- and ELK-related kinase, HEK3
2	B	Ephrin type-A receptor 8	polymer	325	36778.6	1	UniProt (P29322) Pfam (PF14575) Pfam (PF07714) In PDB	Homo sapiens (human)	Tyrosine-protein kinase receptor EEK, EPH- and ELK-related kinase, HEK3
3	A	SULFATE ION	non-polymer		96.1	2	Chemie (SO4)
4	A, B	BETA-MERCAPTOETHANOL	non-polymer		78.1	2	Chemie (BME)
5	A	GLYCEROL	non-polymer		92.1	1	Chemie (GOL)
6		water	water		18.0	256	Chemie (HOH)

Sequence modifications

A: 602 - 909 (UniProt: P29322)

PDB	External Database	Details
Met 585	-	expression tag
His 586	-	expression tag
His 587	-	expression tag
His 588	-	expression tag
His 589	-	expression tag
His 590	-	expression tag
His 591	-	expression tag
Ser 592	-	expression tag
Ser 593	-	expression tag
Gly 594	-	expression tag
Arg 595	-	expression tag
Glu 596	-	expression tag
Asn 597	-	expression tag
Leu 598	-	expression tag
Tyr 599	-	expression tag
Phe 600	-	expression tag
Gln 601	-	expression tag

B: 602 - 909 (UniProt: P29322)

PDB	External Database	Details
Met 585	-	expression tag
His 586	-	expression tag
His 587	-	expression tag
His 588	-	expression tag
His 589	-	expression tag
His 590	-	expression tag
His 591	-	expression tag
Ser 592	-	expression tag
Ser 593	-	expression tag
Gly 594	-	expression tag
Arg 595	-	expression tag
Glu 596	-	expression tag
Asn 597	-	expression tag
Leu 598	-	expression tag
Tyr 599	-	expression tag
Phe 600	-	expression tag
Gln 601	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	73477.3
Non-Polymers*	Number of molecules	5
	Total formula weight	440.5
All*	Total formula weight	73917.7

*Water molecules are not included.