3KQE
Factor xa in complex with the inhibitor 3-methyl-1-(3-(5- oxo-4,5-dihydro-1h-1,2,4-triazol-3-yl)phenyl)-6-(2'- (pyrrolidin-1-ylmethyl)biphenyl-4-yl)-5,6-dihydro-1h- pyrazolo[3,4-c]pyridin-7(4h)-one
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | factor Xa heavy chain | polymer | 234 | 26447.1 | 1 | UniProt (P00742) Pfam (PF00089) In PDB | Homo sapiens (human) | |
| 2 | L | factor Xa light chain | polymer | 52 | 5589.2 | 1 | UniProt (P00742) Pfam (PF14670) In PDB | Homo sapiens (human) | |
| 3 | A | 3-METHYL-1-(3-(5-OXO-4,5-DIHYDRO-1H-1,2,4-TRIAZOL-3-YL)PHENYL)-6-(2'-(PYRROLIDIN-1-YLMETHYL)BIPHENYL-4-YL)-5,6-DIHYDRO-1H-PYRAZOLO[3,4-C]PYRIDIN-7(4H)-ONE | non-polymer | 545.6 | 1 | Chemie (LGM) | |||
| 4 | A | SODIUM ION | non-polymer | 23.0 | 2 | Chemie (NA) | |||
| 5 | water | water | 18.0 | 80 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 32036.3 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 591.6 | |
| All* | Total formula weight | 32628.0 |
