3K22
Glucocorticoid Receptor with Bound alaninamide 10 with TIF2 peptide
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B | Glucocorticoid receptor | polymer | 259 | 29985.8 | 2 | UniProt (P04150) Pfam (PF00104) In PDB | Homo sapiens (human) | GR, Nuclear receptor subfamily 3 group C member 1 |
2 | H, D | Transcriptional Intermediary Factor 2 | polymer | 12 | 1478.8 | 2 | UniProt (by SIFTS) (Q15596) In PDB | ||
3 | A, B | N-[(1R)-2-amino-1-methyl-2-oxoethyl]-3-(6-methyl-4-{[3,3,3-trifluoro-2-hydroxy-2-(trifluoromethyl)propyl]amino}-1H-indazol-1-yl)benzamide | non-polymer | 517.4 | 2 | Chemie (JZS) | |||
4 | A, B | hexyl beta-D-glucopyranoside | non-polymer | 264.3 | 3 | Chemie (JZR) | |||
5 | water | water | 18.0 | 44 | Chemie (HOH) |
Sequence modifications
A, B: 521 - 777 (UniProt: P04150)
PDB | External Database | Details |
---|---|---|
Gly 519 | - | expression tag |
Ser 520 | - | expression tag |
Tyr 602 | Phe 602 | engineered mutation |
Gly 638 | Cys 638 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 4 |
Total formula weight | 62929.2 | |
Non-Polymers* | Number of molecules | 5 |
Total formula weight | 1827.8 | |
All* | Total formula weight | 64757.0 |