3IXS

Ring1B C-terminal domain/RYBP C-terminal domain Complex

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, C, E, G, I...	E3 ubiquitin-protein ligase RING2	polymer	111	12614.2	6	UniProt (Q99496) Pfam (PF16207) In PDB	Homo sapiens (human)	RING finger protein 2, RING finger protein 1B, RING1b, RING finger protein BAP-1, DinG protein, Huntingtin-interacting protein 2-interacting protein 3, HIP2-interacting protein 3
2	B, D, F, H, J...	RING1 and YY1-binding protein	polymer	37	4107.7	6	UniProt (Q8N488) Pfam (PF17219) In PDB	Homo sapiens (human)	Death effector domain-associated factor, DED-associated factor, YY1 and E4TF1-associated factor 1, Apoptin-associating protein 1, APAP-1
3	A, C, E, H	1,2-ETHANEDIOL	non-polymer		62.1	4	Chemie (EDO)
4	C	2-[N-CYCLOHEXYLAMINO]ETHANE SULFONIC ACID	non-polymer		207.3	1	Chemie (NHE)
5		water	water		18.0	421	Chemie (HOH)

Sequence modifications

A, C, E, G, I, K: 223 - 333 (UniProt: Q99496)

PDB	External Database	Details
Asp 306	Asn 306	engineered mutation

B, D, F, H, J, L: 145 - 179 (UniProt: Q8N488)

PDB	External Database	Details
Gly 143	-	expression tag
Thr 144	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	12
	Total formula weight	100331.4
Non-Polymers*	Number of molecules	5
	Total formula weight	455.6
All*	Total formula weight	100787.0

*Water molecules are not included.