3HA5

Crystal structure of HMA (MMAA4) from mycobacterium tuberculosis complexed with sinefungin

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	METHOXY MYCOLIC ACID SYNTHASE 4	polymer	318	36521.3	1	UniProt (Q79FX8) Pfam (PF02353) In PDB	Mycobacterium tuberculosis	MMAA4 (METHYL MYCOLIC ACID SYNTHASE 4) (MMA4) (HYDROXY MYCOLIC ACID SYNTHASE)
2	A	SINEFUNGIN	non-polymer		381.4	1	Chemie (SFG)
3		water	water		18.0	67	Chemie (HOH)

Sequence modifications

A: 4 - 301 (UniProt: Q79FX8)

PDB	External Database	Details
Met -16	-	expression tag
Gly -15	-	expression tag
Ser -14	-	expression tag
Ser -13	-	expression tag
His -12	-	expression tag
Tyr -11	-	expression tag
His -10	-	expression tag
His -9	-	expression tag
His -8	-	expression tag
His -7	-	expression tag
Ser -6	-	expression tag
Ser -5	-	expression tag
Gly -4	-	expression tag
Leu -3	-	expression tag
Val -2	-	expression tag
Pro -1	-	expression tag
Arg 0	-	expression tag
Gly 1	-	expression tag
Ser 2	-	expression tag
His 3	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	36521.3
Non-Polymers*	Number of molecules	1
	Total formula weight	381.4
All*	Total formula weight	36902.7

*Water molecules are not included.