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3H1V

Human glucokinase in complex with a synthetic activator

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1XGlucokinasepolymer45150610.51UniProt (P35557)
Pfam (PF00349)
Pfam (PF03727)
In PDB
Homo sapiens (Human)Hexokinase type IV, HK IV, Hexokinase-4, HK4, Hexokinase-D
2Xalpha-D-glucopyranosenon-polymer180.21Chemie (GLC)
3X1-({5-[4-(methylsulfonyl)phenoxy]-2-pyridin-2-yl-1H-benzimidazol-6-yl}methyl)pyrrolidine-2,5-dionenon-polymer476.51Chemie (TK1)
4XSODIUM IONnon-polymer23.01Chemie (NA)
5waterwater18.0120Chemie (HOH)
Sequence modifications
X: 16 - 465 (UniProt: P35557)
PDBExternal DatabaseDetails
Met 15-initiating methionine
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight50610.5
Non-Polymers*Number of molecules3
Total formula weight679.7
All*Total formula weight51290.2
*Water molecules are not included.

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PDB entries from 2024-05-08

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