3G3M

Crystal Structure of Human Orotidine 5'-monophosphate Decarboxylase Covalently Modified by 5-fluoro-6-iodo-UMP

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	Uridine 5'-monophosphate synthase	polymer	279	30488.2	1	UniProt (P11172) Pfam (PF00215) In PDB	Homo sapiens (Human)	UMP synthase
2	A	5-FLUORO-URIDINE-5'-MONOPHOSPHATE	non-polymer		342.2	1	Chemie (5FU)
3		water	water		18.0	272	Chemie (HOH)

Sequence modifications

A: 34 - 291 (UniProt: P11172)

PDB	External Database	Details
Met 13	-	expression tag
Gly 14	-	expression tag
Ser 15	-	expression tag
Ser 16	-	expression tag
His 17	-	expression tag
His 18	-	expression tag
His 19	-	expression tag
His 20	-	expression tag
His 21	-	expression tag
His 22	-	expression tag
Ser 23	-	expression tag
Ser 24	-	expression tag
Gly 25	-	expression tag
Leu 26	-	expression tag
Val 27	-	expression tag
Pro 28	-	expression tag
Arg 29	-	expression tag
Gly 30	-	expression tag
Ser 31	-	expression tag
His 32	-	expression tag
Met 33	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	30488.2
Non-Polymers*	Number of molecules	1
	Total formula weight	342.2
All*	Total formula weight	30830.3

*Water molecules are not included.