3EGY
Crystal Structure of Human Thymidyalte Synthase A191K with Loop 181-197 stabilized in the inactive conformation
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | X | Thymidylate synthase | polymer | 313 | 36125.5 | 1 | UniProt (P04818) Pfam (PF00303) In PDB | Homo sapiens (human) | TSase, TS |
| 2 | X | SULFATE ION | non-polymer | 96.1 | 2 | Chemie (SO4) | |||
| 3 | X | 1,2-ETHANEDIOL | non-polymer | 62.1 | 1 | Chemie (EDO) | |||
| 4 | water | water | 18.0 | 125 | Chemie (HOH) |
Sequence modifications
X: 1 - 313 (UniProt: P04818)
| PDB | External Database | Details |
|---|---|---|
| Lys 191 | Ala 191 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 36125.5 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 254.2 | |
| All* | Total formula weight | 36379.7 |
