3EGI
Methyltransferase domain of human trimethylguanosine synthase TGS1 bound to m7GpppA (inactive form)
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B, C, D | Trimethylguanosine synthase homolog | polymer | 206 | 22795.6 | 4 | UniProt (Q96RS0) Pfam (PF09445) In PDB | Homo sapiens (Human) | Nuclear receptor coactivator 6-interacting protein, PRIP-interacting protein with methyltransferase motif, PIPMT, PIMT, CLL-associated antigen KW-2, Hepatocellular carcinoma-associated antigen 137 |
2 | A, B, C, D | ADENOSINE-5'-DIPHOSPHATE | non-polymer | 427.2 | 4 | Chemie (ADP) | |||
3 | water | water | 18.0 | 631 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 653 - 853 (UniProt: Q96RS0)
PDB | External Database | Details |
---|---|---|
Gly 648 | - | EXPRESSION TAG |
Pro 649 | - | EXPRESSION TAG |
Leu 650 | - | EXPRESSION TAG |
Gly 651 | - | EXPRESSION TAG |
Ser 652 | - | EXPRESSION TAG |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 4 |
Total formula weight | 91182.2 | |
Non-Polymers* | Number of molecules | 4 |
Total formula weight | 1708.8 | |
All* | Total formula weight | 92891.0 |