3DCG

Crystal Structure of the HIV Vif BC-box in Complex with Human ElonginB and ElonginC

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, C	Transcription elongation factor B polypeptide 2	polymer	118	13147.8	2	UniProt (Q15370) Pfam (PF00240) In PDB	Homo sapiens (Human)	ElonginB, RNA polymerase II transcription factor SIII subunit B, SIII p18, Elongin-B, EloB, Elongin 18 kDa subunit
2	B, D	Transcription elongation factor B polypeptide 1	polymer	97	10974.6	2	UniProt (Q15369) Pfam (PF03931) In PDB	Homo sapiens (Human)	ElonginC, RNA polymerase II transcription factor SIII subunit C, SIII p15, Elongin-C, EloC, Elongin 15 kDa subunit
3	E, F	Virion infectivity factor	polymer	39	4448.3	2	UniProt (P12504) In PDB	Human immunodeficiency virus type 1 (NEW YORK-5 ISOLATE) (HIV-1)	Vif, SOR protein, Virion infectivity factor p17, Virion infectivity factor p7
4		water	water		18.0	150	Chemie (HOH)

Sequence modifications

B, D: 17 - 112 (UniProt: Q15369)

PDB	External Database	Details
Met 16	-	initiating methionine

E, F: 139 - 176 (UniProt: P12504)

PDB	External Database	Details
Ser 138	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	6
	Total formula weight	57141.4
All*	Total formula weight	57141.4

*Water molecules are not included.