3CYO
Structure of a longer thermalstable core domain of HIV-1 GP41 containing the enfuvirtide resistance mutation N43D and complementary mutation E137K
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | Transmembrane protein | polymer | 86 | 9975.2 | 1 | UniProt (Q70626) Pfam (PF00517) UniProt (by SIFTS) (Q53I19) In PDB | Human immunodeficiency virus type 1 | TM, GLYCOPROTEIN41, GP41 |
2 | water | water | 18.0 | 27 | Chemie (HOH) |
Sequence modifications
A: 1 - 44 (UniProt: Q70626)
A: 51 - 86 (UniProt: Q70626)
PDB | External Database | Details |
---|---|---|
Asp 19 | Asn 554 | engineered mutation |
PDB | External Database | Details |
---|---|---|
Ser 45 | - | linker |
Gly 46 | - | linker |
Gly 47 | - | linker |
Arg 48 | - | linker |
Gly 49 | - | linker |
Gly 50 | - | linker |
Lys 71 | Glu 648 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 1 |
Total formula weight | 9975.2 | |
All* | Total formula weight | 9975.2 |