3BX5
P38 alpha map kinase complexed with BMS-640994
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | Mitogen-activated protein kinase 14 | polymer | 366 | 42105.0 | 1 | UniProt (Q16539) Pfam (PF00069) In PDB | Homo sapiens (human) | Mitogen-activated protein kinase p38 alpha, MAP kinase p38 alpha, Cytokine suppressive anti-inflammatory drug-binding protein, CSAID-binding protein, CSBP, MAX-interacting protein 2, MAP kinase MXI2, SAPK2A |
2 | A | N-[2-methyl-5-(methylcarbamoyl)phenyl]-2-{[(1R)-1-methylpropyl]amino}-1,3-thiazole-5-carboxamide | non-polymer | 346.4 | 1 | Chemie (304) | |||
3 | water | water | 18.0 | 36 | Chemie (HOH) |
Sequence modifications
A: 2 - 360 (UniProt: Q16539)
PDB | External Database | Details |
---|---|---|
Met -5 | - | expression tag |
Ala -4 | - | expression tag |
His -3 | - | expression tag |
His -2 | - | expression tag |
His -1 | - | expression tag |
His 0 | - | expression tag |
His 1 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 1 |
Total formula weight | 42105.0 | |
Non-Polymers* | Number of molecules | 1 |
Total formula weight | 346.4 | |
All* | Total formula weight | 42451.5 |