3BPF
Crystal Structure of Falcipain-2 with Its inhibitor, E64
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B, C, D | Cysteine protease falcipain-2 | polymer | 241 | 27186.7 | 4 | UniProt (Q9NBD4) Pfam (PF00112) UniProt (by SIFTS) (Q8I6U4) In PDB | Plasmodium falciparum | |
2 | A, B, C, D | N-[N-[1-HYDROXYCARBOXYETHYL-CARBONYL]LEUCYLAMINO-BUTYL]-GUANIDINE | non-polymer | 360.4 | 4 | Chemie (E64) | |||
3 | C | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) | |||
4 | water | water | 18.0 | 42 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 1 - 241 (UniProt: Q9NBD4)
PDB | External Database | Details |
---|---|---|
Gln 171 | Glu 414 | SEE REMARK 999 |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 4 |
Total formula weight | 108746.7 | |
Non-Polymers* | Number of molecules | 5 |
Total formula weight | 1533.8 | |
All* | Total formula weight | 110280.5 |