3A8Y

Crystal structure of the complex between the BAG5 BD5 and Hsp70 NBD

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B	Heat shock 70 kDa protein 1	polymer	392	43150.8	2	UniProt (P08107) Pfam (PF00012) UniProt (by SIFTS) (P0DMV8) In PDB	Homo sapiens (human)	HSP70.1, HSP70-1/HSP70-2
2	C, D	BAG family molecular chaperone regulator 5	polymer	142	16170.3	2	UniProt (Q9UL15) Pfam (PF02179) In PDB	Homo sapiens (human)	BAG-5, Bcl-2-associated athanogene 5
3	A, B	2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL	non-polymer		122.1	2	Chemie (TRS)
4		water	water		18.0	522	Chemie (HOH)

Sequence modifications

A, B: 1 - 388 (UniProt: P08107)

PDB	External Database	Details
Gly -3	-	expression tag
Ser -2	-	expression tag
Phe -1	-	expression tag
Thr 0	-	expression tag

C, D: 341 - 447 (UniProt: Q9UL15)

PDB	External Database	Details
Gly 334	-	expression tag
Ser 335	-	expression tag
Ser 336	-	expression tag
Gly 337	-	expression tag
Ser 338	-	expression tag
Ser 339	-	expression tag
Gly 340	-	expression tag
Cys 448	-	expression tag
Lys 449	-	expression tag
Ala 450	-	expression tag
Ala 451	-	expression tag
Arg 452	-	expression tag
Lys 453	-	expression tag
Gln 454	-	expression tag
Ala 455	-	expression tag
Val 456	-	expression tag
Arg 457	-	expression tag
Leu 458	-	expression tag
Ala 459	-	expression tag
Gln 460	-	expression tag
Asn 461	-	expression tag
Ile 462	-	expression tag
Leu 463	-	expression tag
Ser 464	-	expression tag
Tyr 465	-	expression tag
Leu 466	-	expression tag
Asp 467	-	expression tag
Leu 468	-	expression tag
Lys 469	-	expression tag
Ser 470	-	expression tag
Asp 471	-	expression tag
Glu 472	-	expression tag
Trp 473	-	expression tag
Glu 474	-	expression tag
Tyr 475	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	118642.1
Non-Polymers*	Number of molecules	2
	Total formula weight	244.3
All*	Total formula weight	118886.4

*Water molecules are not included.