3A7Q
Structural basis for specific recognition of reelin by its receptors
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Reelin | polymer | 725 | 81317.1 | 1 | UniProt (Q60841) Pfam (PF21471) In PDB | Mus musculus (mouse) | Reeler protein |
| 2 | B | Low-density lipoprotein receptor-related protein 8 | polymer | 44 | 5082.4 | 1 | UniProt (Q14114) Pfam (PF00057) In PDB | Homo sapiens (human) | Apolipoprotein E receptor 2 |
| 3 | C | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 1 | In PDB GlyTouCan (G42666HT) | |||
| 4 | A | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 3 | Chemie (NAG) | |||
| 5 | A, B | CALCIUM ION | non-polymer | 40.1 | 5 | Chemie (CA) | |||
| 6 | A | ZINC ION | non-polymer | 65.4 | 1 | Chemie (ZN) | |||
| 7 | water | water | 18.0 | 19 | Chemie (HOH) |
Sequence modifications
A: 1948 - 2661 (UniProt: Q60841)
B: 42 - 83 (UniProt: Q14114)
| PDB | External Database | Details |
|---|---|---|
| Gly 1946 | - | expression tag |
| Arg 1947 | - | expression tag |
| Ala 2101 | Cys 2101 | engineered mutation |
| Ser 2662 | - | expression tag |
| Arg 2663 | - | expression tag |
| Leu 2664 | - | expression tag |
| Glu 2665 | - | expression tag |
| Asn 2666 | - | expression tag |
| Leu 2667 | - | expression tag |
| Tyr 2668 | - | expression tag |
| Phe 2669 | - | expression tag |
| Gln 2670 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Gly 40 | - | expression tag |
| Ser 41 | - | expression tag |
| Glu 46 | Asp 46 | SEE REMARK 999 |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 86399.5 | |
| Branched | Number of molecules | 1 |
| Total formula weight | 424.4 | |
| Non-Polymers* | Number of molecules | 9 |
| Total formula weight | 929.4 | |
| All* | Total formula weight | 87753.3 |
