2YA4

Crystal structure of Streptococcus pneumoniae NanA (TIGR4)

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B	NEURAMINIDASE A	polymer	493	55346.7	2	UniProt (B2DJD9) Pfam (PF13088) UniProt (by SIFTS) (P62575) In PDB	STREPTOCOCCUS PNEUMONIAE	NANA
2	A, B	FORMIC ACID	non-polymer		46.0	10	Chemie (FMT)
3	A, B	1,2-ETHANEDIOL	non-polymer		62.1	6	Chemie (EDO)
4	A, B	CHLORIDE ION	non-polymer		35.5	2	Chemie (CL)
5		water	water		18.0	838	Chemie (HOH)

Sequence modifications

A, B: 303 - 777 (UniProt: B2DJD9)

PDB	External Database	Details
Ala 285	-	expression tag
His 286	-	expression tag
His 287	-	expression tag
His 288	-	expression tag
His 289	-	expression tag
His 290	-	expression tag
His 291	-	expression tag
Ser 292	-	expression tag
Ser 293	-	expression tag
Gly 294	-	expression tag
Leu 295	-	expression tag
Glu 296	-	expression tag
Val 297	-	expression tag
Leu 298	-	expression tag
Phe 299	-	expression tag
Gln 300	-	expression tag
Gly 301	-	expression tag
Pro 302	-	expression tag
Lys 440	Glu 417	SEE REMARK 999
Asp 584	Asn 561	SEE REMARK 999

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	110693.4
Non-Polymers*	Number of molecules	18
	Total formula weight	903.6
All*	Total formula weight	111596.9

*Water molecules are not included.