2XR5
Crystal structure of the complex of the carbohydrate recognition domain of human DC-SIGN with pseudo dimannoside mimic.
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | CD209 ANTIGEN | polymer | 166 | 19032.0 | 1 | UniProt (Q9NNX6) Pfam (PF00059) In PDB | HOMO SAPIENS (HUMAN) | DC-SIGN, DENDRITIC CELL-SPECIFIC ICAM-3-GRABBING NON-INTEGRIN 1, DC-SIGN1, C-TYPE LECTIN DOMAIN FAMILY 4 MEMBER L, CD209, MDC-SIGN1A TYPE I |
2 | A | alpha-D-mannopyranose | non-polymer | 180.2 | 1 | Chemie (MAN) | |||
3 | A | dimethyl (1S,2S,4S,5S)-4,5-dihydroxycyclohexane-1,2-dicarboxylate | non-polymer | 232.2 | 1 | Chemie (07B) | |||
4 | A | ETHANOLAMINE | non-polymer | 61.1 | 1 | Chemie (ETA) | |||
5 | A | CALCIUM ION | non-polymer | 40.1 | 3 | Chemie (CA) | |||
6 | A | CHLORIDE ION | non-polymer | 35.5 | 3 | Chemie (CL) | |||
7 | water | water | 18.0 | 166 | Chemie (HOH) |
Sequence modifications
A: 254 - 404 (UniProt: Q9NNX6)
PDB | External Database | Details |
---|---|---|
Met 239 | - | expression tag |
Ala 240 | - | expression tag |
Ser 241 | - | expression tag |
Trp 242 | - | expression tag |
Ser 243 | - | expression tag |
His 244 | - | expression tag |
Pro 245 | - | expression tag |
Gln 246 | - | expression tag |
Phe 247 | - | expression tag |
Glu 248 | - | expression tag |
Lys 249 | - | expression tag |
Ile 250 | - | expression tag |
Glu 251 | - | expression tag |
Gly 252 | - | expression tag |
Arg 253 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 1 |
Total formula weight | 19032.0 | |
Non-Polymers* | Number of molecules | 9 |
Total formula weight | 700.1 | |
All* | Total formula weight | 19732.0 |