2X7Z

Crystal Structure of the SAP97 PDZ2 I342W C378A mutant protein domain

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	DISKS LARGE HOMOLOG 1	polymer	99	10484.0	1	UniProt (Q12959) Pfam (PF00595) In PDB	HOMO SAPIENS (HUMAN)	SYNAPSE-ASSOCIATED PROTEIN 97, SAP97, SAP-97, HDLG
2	A	AMMONIUM ION	non-polymer		18.0	1	Chemie (NH4)
3	A	IMIDAZOLE	non-polymer		69.1	1	Chemie (IMD)
4		water	water		18.0	82	Chemie (HOH)

Sequence modifications

A: 309 - 310 (PDB: 2X7Z)
A: 311 - 407 (UniProt: Q12959)

PDB	External Database	Details
Trp 342	Ile 291	engineered mutation
Ala 378	Cys 327	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	10484.0
Non-Polymers*	Number of molecules	2
	Total formula weight	87.1
All*	Total formula weight	10571.1

*Water molecules are not included.