2WFX
Crystal structure of the complex between human hedgehog-interacting protein HIP and Sonic Hedgehog in the presence of calcium
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | SONIC HEDGEHOG PROTEIN N-PRODUCT | polymer | 152 | 17366.4 | 1 | UniProt (Q62226) Pfam (PF01085) In PDB | MUS MUSCULUS (MOUSE) | SONIC HEDGEHOG SHH, SONIC HEDGEHOG PROTEIN, HHG-1, SHH |
| 2 | B | HEDGEHOG-INTERACTING PROTEIN | polymer | 457 | 50971.8 | 1 | UniProt (Q96QV1) Pfam (PF07995) Pfam (PF07974) In PDB | HOMO SAPIENS (HUMAN) | HHIP, HIP, HEDGEHOG-INTERACTING PROTEIN HIP |
| 3 | A | ZINC ION | non-polymer | 65.4 | 1 | Chemie (ZN) | |||
| 4 | A, B | CALCIUM ION | non-polymer | 40.1 | 3 | Chemie (CA) | |||
| 5 | B | SODIUM ION | non-polymer | 23.0 | 3 | Chemie (NA) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 68338.2 | |
| Non-Polymers* | Number of molecules | 7 |
| Total formula weight | 254.6 | |
| All* | Total formula weight | 68592.9 |
