2W1E
Structure determination of Aurora Kinase in complex with inhibitor
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | SERINE/THREONINE-PROTEIN KINASE 6 | polymer | 275 | 32157.9 | 1 | UniProt (O14965) Pfam (PF00069) In PDB | HOMO SAPIENS (HUMAN) | AURORA KINASE A, SERINE/THREONINE KINASE 15, AURORA/IPL1-RELATED KINASE 1, BREAST TUMOR-AMPLIFIED KINASE |
| 2 | A | 4-[(2-{4-[(PHENYLCARBAMOYL)AMINO]-1H-PYRAZOL-3-YL}-1H-BENZIMIDAZOL-5-YL)METHYL]MORPHOLIN-4-IUM | non-polymer | 418.5 | 1 | Chemie (L0E) | |||
| 3 | water | water | 18.0 | 4 | Chemie (HOH) |
Sequence modifications
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 32157.9 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 418.5 | |
| All* | Total formula weight | 32576.4 |
