2VDE

Crystal Structure of the Open State of TolC Outer Membrane Component of Mutlidrug Efflux Pumps

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C	OUTER MEMBRANE PROTEIN TOLC	polymer	460	50623.0	3	UniProt (P02930) Pfam (PF02321) In PDB	ESCHERICHIA COLI	TOLC
2	A, B, C	CHLORIDE ION	non-polymer		35.5	4	Chemie (CL)

Sequence modifications

A, B, C: 1 - 450 (UniProt: P02930)

PDB	External Database	Details
Arg 2	Lys 2	conflict
Leu 191	Val 191	engineered mutation
Phe 384	Tyr 384	engineered mutation
Glu 389	Arg 389	engineered mutation

A, B, C: 451 - 460 (PDB: 2VDE)

Contents of the asymmetric unit

Polymers	Number of chains	3
	Total formula weight	151869.0
Non-Polymers*	Number of molecules	4
	Total formula weight	141.8
All*	Total formula weight	152010.8

*Water molecules are not included.