2V7G
Crystal Structure of an Engineered Urocanase Tetramer
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B, C, D | UROCANATE HYDRATASE | polymer | 557 | 60811.7 | 4 | UniProt (P25080) Pfam (PF17391) Pfam (PF01175) Pfam (PF17392) In PDB | PSEUDOMONAS PUTIDA | UROCANASE, IMIDAZOLONEPROPIONATE HYDROLASE |
2 | A, B, C | ACETATE ION | non-polymer | 59.0 | 7 | Chemie (ACT) | |||
3 | A, B, D | GLYCEROL | non-polymer | 92.1 | 9 | Chemie (GOL) | |||
4 | A, B, C, D | NICOTINAMIDE-ADENINE-DINUCLEOTIDE | non-polymer | 663.4 | 4 | Chemie (NAD) | |||
5 | water | water | 18.0 | 1310 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 1 - 1 (PDB: 2V7G)
A, B, C, D: 2 - 557 (UniProt: P25080)
A, B, C, D: 2 - 557 (UniProt: P25080)
PDB | External Database | Details |
---|---|---|
Ser 198 | Cys 197 | engineered mutation |
Ile 277 | Ala 276 | engineered mutation |
Ile 291 | Glu 290 | engineered mutation |
Ala 301 | Gln 300 | engineered mutation |
Ser 164 | Thr 163 | conflict |
Leu 165 | Val 164 | conflict |
Gly 167 | Ala 166 | conflict |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 4 |
Total formula weight | 243246.7 | |
Non-Polymers* | Number of molecules | 20 |
Total formula weight | 3895.9 | |
All* | Total formula weight | 247142.6 |