2Q54
Crystal structure of KB73 bound to HIV-1 protease
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B | Protease | polymer | 99 | 10815.8 | 2 | UniProt (O38732) Pfam (PF00077) UniProt (by SIFTS) (O38710) In PDB | Human immunodeficiency virus 1 | |
| 2 | A | PHOSPHATE ION | non-polymer | 95.0 | 2 | Chemie (PO4) | |||
| 3 | A | ACETATE ION | non-polymer | 59.0 | 2 | Chemie (ACT) | |||
| 4 | B | N~2~-ACETYL-N-[(1S,3S,4S)-4-({[(5S)-3-(3-ACETYLPHENYL)-2-OXO-1,3-OXAZOLIDIN-5-YL]CARBONYL}AMINO)-1-BENZYL-3-HYDROXY-5-PHENYLPENTYL]-L-VALINAMIDE | non-polymer | 656.8 | 1 | Chemie (MU1) | |||
| 5 | water | water | 18.0 | 135 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 99 (UniProt: O38732)
| PDB | External Database | Details |
|---|---|---|
| Lys 7 | Gln 7 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 21631.6 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 964.8 | |
| All* | Total formula weight | 22596.4 |
