2OP9
Substrate Specificity Profiling and Identification of a New Class of Inhibitor for the Major Protease of the SARS Coronavirus
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B | Replicase polyprotein 1ab (pp1ab, ORF1AB) 3C-like proteinase (3CL-PRO, 3CLp) | polymer | 302 | 33415.1 | 2 | UniProt (P59641) Pfam (PF05409) UniProt (by SIFTS) (P0C6X7) In PDB | SARS coronavirus | |
| 2 | A, B | NALPHA-[(BENZYLOXY)CARBONYL]-N-[(1R)-4-HYDROXY-1-METHYL-2-OXOBUTYL]-L-PHENYLALANINAMIDE | non-polymer | 398.5 | 2 | Chemie (WR1) | |||
| 3 | water | water | 18.0 | 491 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 301 (UniProt: P59641)
| PDB | External Database | Details |
|---|---|---|
| Ala 0 | - | cloning artifact |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 66830.3 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 796.9 | |
| All* | Total formula weight | 67627.2 |
