2NXZ
HIV-1 gp120 Envelope Glycoprotein (T257S, S334A, S375W) Complexed with CD4 and Antibody 17b
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | ENVELOPE GLYCOPROTEIN GP120 | polymer | 317 | 35125.8 | 1 | UniProt (Q8QDX5) Pfam (PF00516) UniProt (by SIFTS) (P19551) In PDB | Human immunodeficiency virus 1 | |
| 2 | B | T-cell surface glycoprotein CD4 | polymer | 184 | 20419.3 | 1 | UniProt (P01730) Pfam (PF00047) Pfam (PF05790) In PDB | Homo sapiens (human) | T-cell surface antigen T4/Leu-3 |
| 3 | C | ANTIBODY 17B, LIGHT CHAIN | polymer | 214 | 23399.9 | 1 | UniProt (Q6P5S8) Pfam (PF07686) Pfam (PF07654) In PDB | Homo sapiens (human) | |
| 4 | D | ANTIBODY 17B, HEAVY CHAIN | polymer | 229 | 24457.4 | 1 | UniProt (Q6PJA4) In PDB | Homo sapiens (human) | |
| 5 | E | beta-D-fructofuranose-(2-1)-alpha-D-glucopyranose | branched | 342.3 | 1 | In PDB BIRD (PRD_900003) | sucrose | ||
| 6 | A | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 13 | Chemie (NAG) | |||
| 7 | A, C | 1,2-ETHANEDIOL | non-polymer | 62.1 | 3 | Chemie (EDO) | |||
| 8 | A | HEXANE-1,6-DIOL | non-polymer | 118.2 | 1 | Chemie (HEZ) | |||
| 9 | B | ISOPROPYL ALCOHOL | non-polymer | 60.1 | 1 | Chemie (IPA) | |||
| 10 | water | water | 18.0 | 563 | Chemie (HOH) |
Sequence modifications
B: 1001 - 1183 (UniProt: P01730)
| PDB | External Database | Details |
|---|---|---|
| Met 1000 | - | initiating methionine |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 103402.3 | |
| Branched | Number of molecules | 1 |
| Total formula weight | 342.3 | |
| Non-Polymers* | Number of molecules | 18 |
| Total formula weight | 3240.2 | |
| All* | Total formula weight | 106984.8 |
