2NTJ
Mycobacterium tuberculosis InhA bound with PTH-NAD adduct
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B | Enoyl-[acyl-carrier-protein] reductase [NADH | polymer | 268 | 28393.6 | 2 | UniProt (P0A5Y6) Pfam (PF13561) UniProt (by SIFTS) (P9WGR1) In PDB | Mycobacterium tuberculosis | NADH- dependent enoyl-ACP reductase |
| 2 | A, B | {(2R,3S,4R,5R)-5-[(4S)-3-(AMINOCARBONYL)-4-(2-PROPYLISONICOTINOYL)PYRIDIN-1(4H)-YL]-3,4-DIHYDROXYTETRAHYDROFURAN-2-YL}M ETHYL [(2R,3S,4R,5R)-5-(6-AMINO-9H-PURIN-9-YL)-3,4-DIHYDROXYTETRAHYDROFURAN-2-YL]METHYL DIHYDROGEN DIPHOSPHATE | non-polymer | 812.6 | 2 | Chemie (P1H) | |||
| 3 | water | water | 18.0 | 83 | Chemie (HOH) |
Sequence modifications
A, B: 3 - 269 (UniProt: P0A5Y6)
| PDB | External Database | Details |
|---|---|---|
| Ala 2 | Asp 2 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 56787.1 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 1625.2 | |
| All* | Total formula weight | 58412.4 |
