2N9Y

Structure of the Integrin alphaIIb-beta3(A711P) Transmembrane Complex

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	Integrin alpha-IIb	polymer	42	4783.9	1	UniProt (P08514) Pfam (PF00357) In PDB	Homo sapiens (human)	GPalpha IIb, GPIIb, Platelet membrane glycoprotein IIb, Integrin alpha-IIb heavy chain, Integrin alpha-IIb light chain, form 1, Integrin alpha-IIb light chain, form 2
2	B	Integrin beta-3	polymer	43	4744.9	1	UniProt (P05106) In PDB	Homo sapiens (human)	Platelet membrane glycoprotein IIIa, GPIIIa

Sequence modifications

A: 958 - 998 (UniProt: P08514)

PDB	External Database	Details
Gly 957	-	EXPRESSION TAG
Cys 963	Ala 994	ENGINEERED MUTATION

B: 686 - 727 (UniProt: P05106)

PDB	External Database	Details
Gly 685	-	EXPRESSION TAG
Ser 687	Cys 713	ENGINEERED MUTATION
Cys 690	Gly 716	ENGINEERED MUTATION
Pro 711	Ala 737	ENGINEERED MUTATION

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	9528.8
All*	Total formula weight	9528.8

*Water molecules are not included.