2MAW
NMR structures of the alpha7 nAChR transmembrane domain.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Neuronal acetylcholine receptor subunit alpha-7 | polymer | 137 | 14582.0 | 1 | UniProt (P36544) Pfam (PF02932) In PDB | Homo sapiens (human) | CHRNA7-DR1, D-10 |
Sequence modifications
A: 4 - 102 (UniProt: P36544)
A: 108 - 137 (UniProt: P36544)
| PDB | External Database | Details |
|---|---|---|
| Ser 1 | - | expression tag |
| Asn 2 | - | expression tag |
| Ala 3 | - | expression tag |
| Glu 4 | Arg 228 | engineered mutation |
| Glu 5 | Arg 229 | engineered mutation |
| Glu 6 | Thr 230 | engineered mutation |
| Ser 61 | Ala 285 | engineered mutation |
| Ser 66 | Val 290 | engineered mutation |
| Ser 68 | Leu 292 | engineered mutation |
| Glu 102 | Lys 326 | engineered mutation |
| PDB | External Database | Details |
|---|---|---|
| Gly 103 | - | linker |
| Gly 104 | - | linker |
| Gly 105 | - | linker |
| Glu 106 | - | linker |
| Gly 107 | - | linker |
| Ile 108 | Val 467 | engineered mutation |
| Glu 137 | Ala 496 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 14582.0 | |
| All* | Total formula weight | 14582.0 |
