2LLY

NMR structures of the transmembrane domains of the nAChR a4 subunit

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	Neuronal acetylcholine receptor subunit alpha-4	polymer	137	15020.9	1	UniProt (P43681) Pfam (PF02932) In PDB	Homo sapiens (human)

Sequence modifications

A: 4 - 103 (UniProt: P43681)

PDB	External Database	Details
Ser 1	-	expression tag
Asn 2	-	expression tag
Ala 3	-	expression tag
Glu 4	Arg 240	engineered mutation
Glu 5	Arg 241	engineered mutation
Ser 65	Leu 301	engineered mutation
Ser 67	Ile 303	engineered mutation
Ser 69	Leu 305	engineered mutation
Glu 100	Arg 336	engineered mutation

A: 109 - 137 (UniProt: P43681)

PDB	External Database	Details
Gly 104	-	linker
Gly 105	-	linker
Gly 106	-	linker
Gly 107	-	linker
Gly 108	-	linker
Glu 137	Met 626	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	15020.9
All*	Total formula weight	15020.9

*Water molecules are not included.