2KN6

Structure of full-length human ASC (Apoptosis-associated speck-like protein containing a CARD)

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	Apoptosis-associated speck-like protein containing a CARD	polymer	215	23823.2	1	UniProt (Q9ULZ3) Pfam (PF02758) Pfam (PF00619) In PDB	Homo sapiens (human)	hASC, PYD and CARD domain-containing protein, Target of methylation-induced silencing 1, Caspase recruitment domain-containing protein 5

Sequence modifications

A: 1 - 195 (UniProt: Q9ULZ3)

PDB	External Database	Details
Met -19	-	expression tag
Gly -18	-	expression tag
Ser -17	-	expression tag
Ser -16	-	expression tag
His -15	-	expression tag
His -14	-	expression tag
His -13	-	expression tag
His -12	-	expression tag
His -11	-	expression tag
His -10	-	expression tag
Ser -9	-	expression tag
Ser -8	-	expression tag
Gly -7	-	expression tag
Leu -6	-	expression tag
Val -5	-	expression tag
Pro -4	-	expression tag
Arg -3	-	expression tag
Gly -2	-	expression tag
Ser -1	-	expression tag
His 0	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	23823.2
All*	Total formula weight	23823.2

*Water molecules are not included.