2J9H
Crystal structure of human glutathione-S-transferase P1-1 cys-free mutant in complex with S-hexylglutathione at 2.4 A resolution
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B | GLUTATHIONE S-TRANSFERASE P | polymer | 209 | 23150.3 | 2 | UniProt (P09211) Pfam (PF02798) Pfam (PF14497) In PDB | HOMO SAPIENS (HUMAN) | GLUTATHIONE-S-TRANSFERASE P1-1, GST CLASS-PI, GSTP1-1 |
| 2 | A, B | S-HEXYLGLUTATHIONE | non-polymer | 392.5 | 2 | Chemie (GTX) | |||
| 3 | water | water | 18.0 | 45 | Chemie (HOH) |
Sequence modifications
A, B: 2 - 210 (UniProt: P09211)
| PDB | External Database | Details |
|---|---|---|
| Ser 15 | Cys 15 | engineered mutation |
| Ala 48 | Cys 48 | engineered mutation |
| Ala 102 | Cys 102 | engineered mutation |
| Ser 170 | Cys 170 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 46300.6 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 785.0 | |
| All* | Total formula weight | 47085.6 |
