2HEV
Crystal structure of the complex between OX40L and OX40
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | F | Tumor necrosis factor ligand superfamily member 4 | polymer | 137 | 15858.0 | 1 | UniProt (P23510) In PDB | Homo sapiens (human) | OX40 ligand, OX40L, Glycoprotein Gp34, TAX transcriptionally-activated glycoprotein 1, CD252 antigen |
2 | R | Tumor necrosis factor receptor superfamily member 4 | polymer | 146 | 15808.8 | 1 | UniProt (P43489) Pfam (PF00020) In PDB | Homo sapiens (human) | OX40L receptor, ACT35 antigen, TAX transcriptionally-activated glycoprotein 1 receptor, CD134 antigen |
3 | F, R | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 2 | Chemie (NAG) | |||
4 | water | water | 18.0 | 87 | Chemie (HOH) |
Sequence modifications
F: 51 - 183 (UniProt: P23510)
R: 29 - 170 (UniProt: P43489)
PDB | External Database | Details |
---|---|---|
Gly 47 | - | cloning artifact |
Ser 48 | - | cloning artifact |
His 49 | - | cloning artifact |
Met 50 | - | cloning artifact |
Asp 90 | Asn 90 | engineered mutation |
Asp 114 | Asn 114 | engineered mutation |
PDB | External Database | Details |
---|---|---|
Gly 25 | - | cloning artifact |
Ser 26 | - | cloning artifact |
His 27 | - | cloning artifact |
Met 28 | - | cloning artifact |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 31666.8 | |
Non-Polymers* | Number of molecules | 2 |
Total formula weight | 442.4 | |
All* | Total formula weight | 32109.2 |