2GKI
Heavy and light chain variable single domains of an anti-DNA binding antibody hydrolyze both double- and single-stranded DNAs without sequence specificity
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B | nuclease | polymer | 291 | 31504.3 | 2 | GenBank (8777863) GenBank (8777865) Pfam (PF07686) UniProt (by SIFTS) (A0N274) In PDB | Mus musculus (house mouse) | |
2 | water | water | 18.0 | 70 | Chemie (HOH) |
Sequence modifications
A, B: 23 - 142 (GenBank: 8777863)
A, B: 159 - 271 (GenBank: 8777865)
PDB | External Database | Details |
---|---|---|
Met 1 | - | cloning artifact |
Lys 2 | - | cloning artifact |
Gln 3 | - | cloning artifact |
Ser 4 | - | cloning artifact |
Thr 5 | - | cloning artifact |
Ile 6 | - | cloning artifact |
Ala 7 | - | cloning artifact |
Leu 8 | - | cloning artifact |
Ala 9 | - | cloning artifact |
Leu 10 | - | cloning artifact |
Leu 11 | - | cloning artifact |
Pro 12 | - | cloning artifact |
Leu 13 | - | cloning artifact |
Leu 14 | - | cloning artifact |
Phe 15 | - | cloning artifact |
Thr 16 | - | cloning artifact |
Pro 17 | - | cloning artifact |
Val 18 | - | cloning artifact |
Thr 19 | - | cloning artifact |
Lys 20 | - | cloning artifact |
Ala 21 | - | cloning artifact |
Arg 22 | - | cloning artifact |
Arg 143 | - | linker |
Gly 144 | - | linker |
Gly 145 | - | linker |
Gly 146 | - | linker |
Gly 147 | - | linker |
Ser 148 | - | linker |
Gly 149 | - | linker |
Gly 150 | - | linker |
Gly 151 | - | linker |
Gly 152 | - | linker |
Ser 153 | - | linker |
Gly 154 | - | linker |
Gly 155 | - | linker |
Gly 156 | - | linker |
Gly 157 | - | linker |
Ser 158 | - | linker |
His 272 | - | cloning artifact |
His 273 | - | cloning artifact |
His 274 | - | cloning artifact |
His 275 | - | cloning artifact |
His 276 | - | cloning artifact |
Gly 277 | - | cloning artifact |
Leu 278 | - | cloning artifact |
Val 279 | - | cloning artifact |
Pro 280 | - | cloning artifact |
Arg 281 | - | cloning artifact |
Gly 282 | - | cloning artifact |
Ser 283 | - | cloning artifact |
Gly 284 | - | cloning artifact |
Asp 285 | - | cloning artifact |
Pro 286 | - | cloning artifact |
Lys 287 | - | cloning artifact |
Ala 288 | - | cloning artifact |
Asp 289 | - | cloning artifact |
Asn 290 | - | cloning artifact |
Lys 291 | - | cloning artifact |
PDB | External Database | Details |
---|---|---|
Leu 160 | Ile 2 | SEE REMARK 999 |
Ser 231 | Pro 73 | SEE REMARK 999 |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 63008.6 | |
All* | Total formula weight | 63008.6 |