2FLS

Crystal structure of Human Glutaredoxin 2 complexed with glutathione

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	Glutaredoxin-2	polymer	132	15299.5	1	UniProt (Q9NS18) Pfam (PF00462) In PDB	Homo sapiens (human)
2	A	GLUTATHIONE	non-polymer		307.3	1	Chemie (GSH)
3		water	water		18.0	53	Chemie (HOH)

Sequence modifications

A: 16 - 124 (UniProt: Q9NS18)

PDB	External Database	Details
Met -7	-	initiating methionine
His -6	-	expression tag
His -5	-	expression tag
His -4	-	expression tag
His -3	-	expression tag
His -2	-	expression tag
His -1	-	expression tag
Ser 0	-	cloning artifact
Ser 1	-	cloning artifact
Gly 2	-	cloning artifact
Val 3	-	cloning artifact
Asp 4	-	cloning artifact
Leu 5	-	cloning artifact
Gly 6	-	cloning artifact
Thr 7	-	cloning artifact
Glu 8	-	cloning artifact
Asn 9	-	cloning artifact
Leu 10	-	cloning artifact
Tyr 11	-	cloning artifact
Phe 12	-	cloning artifact
Gln 13	-	cloning artifact
Ser 14	-	cloning artifact
Met 15	-	cloning artifact

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	15299.5
Non-Polymers*	Number of molecules	1
	Total formula weight	307.3
All*	Total formula weight	15606.9

*Water molecules are not included.