2EIN

Zinc ion binding structure of bovine heart cytochrome C oxidase in the fully oxidized state

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, N	Cytochrome c oxidase subunit 1	polymer	514	57093.9	2	UniProt (P00396) Pfam (PF00115) In PDB	Bos taurus (cattle)	Cytochrome c oxidase polypeptide I
2	B, O	Cytochrome c oxidase subunit 2	polymer	227	26068.4	2	UniProt (P68530) Pfam (PF02790) Pfam (PF00116) In PDB	Bos taurus (cattle)	Cytochrome c oxidase polypeptide II
3	C, P	Cytochrome c oxidase subunit 3	polymer	261	29957.6	2	UniProt (P00415) Pfam (PF00510) In PDB	Bos taurus (cattle)	Cytochrome c oxidase polypeptide III
4	D, Q	Cytochrome c oxidase subunit 4 isoform 1	polymer	147	17179.6	2	UniProt (P00423) Pfam (PF02936) In PDB	Bos taurus (cattle)	Cytochrome c oxidase subunit IV isoform 1, COX IV-1, Cytochrome c oxidase polypeptide IV
5	E, R	Cytochrome c oxidase polypeptide Va	polymer	109	12453.1	2	UniProt (P00426) Pfam (PF02284) In PDB	Bos taurus (cattle)
6	F, S	Cytochrome c oxidase polypeptide Vb	polymer	98	10684.0	2	UniProt (P00428) Pfam (PF01215) In PDB	Bos taurus (cattle)	VI
7	G, T	Cytochrome c oxidase polypeptide VIa-heart	polymer	85	9629.8	2	UniProt (P07471) Pfam (PF02046) In PDB	Bos taurus (cattle)	COXVIAH, Polypeptide VIb
8	H, U	Cytochrome c oxidase subunit VIb isoform 1	polymer	85	10039.2	2	UniProt (P00429) Pfam (PF02297) In PDB	Bos taurus (cattle)	COX VIb-1, Cytochrome c oxidase polypeptide VII, Cytochrome c oxidase subunit AED
9	I, V	Cytochrome c oxidase polypeptide VIc	polymer	73	8537.0	2	UniProt (P04038) Pfam (PF02937) In PDB	Bos taurus (cattle)	STA
10	J, W	Cytochrome c oxidase polypeptide VIIa-heart	polymer	59	6682.7	2	UniProt (P07470) Pfam (PF02238) In PDB	Bos taurus (cattle)	Cytochrome c oxidase subunit VIIa-H, COX VIIa-M, VIIIC
11	K, X	Cytochrome c oxidase polypeptide VIIb	polymer	56	6365.2	2	UniProt (P13183) Pfam (PF05392) In PDB	Bos taurus (cattle)	IHQ
12	L, Y	Cytochrome c oxidase polypeptide VIIc	polymer	47	5449.4	2	UniProt (P00430) Pfam (PF02935) In PDB	Bos taurus (cattle)	VIIIA
13	M, Z	Cytochrome c oxidase polypeptide VIII-heart	polymer	46	4967.8	2	UniProt (P10175) Pfam (PF02285) In PDB	Bos taurus (cattle)	Cytochrome c oxidase subunit 8-1, VIIIb, IX
14	A, N	COPPER (II) ION	non-polymer		63.5	2	Chemie (CU)
15	A, N	MAGNESIUM ION	non-polymer		24.3	2	Chemie (MG)
16	A, N	SODIUM ION	non-polymer		23.0	2	Chemie (NA)
17	A, N	HEME-A	non-polymer		852.8	4	Chemie (HEA)
18	A, L, Y, N, O	TRISTEAROYLGLYCEROL	non-polymer		891.5	6	Chemie (TGL)
19	P, A, N, C	(1R)-2-{[{[(2S)-2,3-DIHYDROXYPROPYL]OXY}(HYDROXY)PHOSPHORYL]OXY}-1-[(PALMITOYLOXY)METHYL]ETHYL (11E)-OCTADEC-11-ENOATE	non-polymer		749.0	8	Chemie (PGV)
20	L, S, T, B, N...	ZINC ION	non-polymer		65.4	14	Chemie (ZN)
21	B, O	DINUCLEAR COPPER ION	non-polymer		127.1	2	Chemie (CUA)
22	B, O	(7R,17E,20E)-4-HYDROXY-N,N,N-TRIMETHYL-9-OXO-7-[(PALMITOYLOXY)METHYL]-3,5,8-TRIOXA-4-PHOSPHAHEXACOSA-17,20-DIEN-1-AMINIUM 4-OXIDE	non-polymer		759.1	2	Chemie (PSC)
23	G, J, P, W, B...	CHOLIC ACID	non-polymer		408.6	8	Chemie (CHD)
24	M, Z, C, P	DECYL-BETA-D-MALTOPYRANOSIDE	non-polymer		482.6	4	Chemie (DMU)
25	G, T, C, P	(1S)-2-{[(2-AMINOETHOXY)(HYDROXY)PHOSPHORYL]OXY}-1-[(STEAROYLOXY)METHYL]ETHYL (5E,8E,11E,14E)-ICOSA-5,8,11,14-TETRAENOATE	non-polymer		768.1	6	Chemie (PEK)
26	G, P, T, C	CARDIOLIPIN	non-polymer		1464.0	4	Chemie (CDL)
27		water	water		18.0	1073	Chemie (HOH)

Contents of the asymmetric unit

Polymers	Number of chains	26
	Total formula weight	410215.6
Non-Polymers*	Number of molecules	64
	Total formula weight	33325.3
All*	Total formula weight	443540.9

*Water molecules are not included.