2D5Y
Aspartate Aminotransferase Mutant MC With Isovaleric Acid
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Aspartate aminotransferase | polymer | 396 | 43664.3 | 1 | UniProt (P00509) Pfam (PF00155) In PDB | Escherichia coli | Transaminase A, ASPAT |
| 2 | A | PYRIDOXAL-5'-PHOSPHATE | non-polymer | 247.1 | 1 | Chemie (PLP) | |||
| 3 | A | ISOVALERIC ACID | non-polymer | 102.1 | 1 | Chemie (IVA) | |||
| 4 | water | water | 18.0 | 162 | Chemie (HOH) |
Sequence modifications
A: 5 - 409 (UniProt: P00509)
| PDB | External Database | Details |
|---|---|---|
| Thr 11 | Ala 7 | engineered mutation |
| Val 293 | Ala 281 | engineered mutation |
| Ser 297 | Asn 285 | engineered mutation |
| Thr 353 | Ile 341 | engineered mutation |
| Phe 361 | Ser 349 | engineered mutation |
| Gly 363 | Ser 351 | engineered mutation |
| Leu 387 | Val 375 | engineered mutation |
| Leu 397 | Met 385 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 43664.3 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 349.3 | |
| All* | Total formula weight | 44013.5 |
