2C4J

Human glutathione-S-transferase M2-2 T210S mutant in complex with glutathione-styrene oxide conjugate

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D	GLUTATHIONE S-TRANSFERASE MU 2	polymer	218	25762.6	4	UniProt (P28161) Pfam (PF02798) Pfam (PF00043) In PDB	HOMO SAPIENS (HUMAN)	GLUTATHIONE TRANSFERASE M2-1, GSTM2-2, GST CLASS-MU 2
2	A, B, C, D	L-GAMMA-GLUTAMYL-S-[(2S)-2-HYDROXY-2-PHENYLETHYL]-L-CYSTEINYLGLYCINE	non-polymer		427.5	4	Chemie (GSO)
3		water	water		18.0	962	Chemie (HOH)

Sequence modifications

A, B, C, D: 1 - 1 (PDB: 2C4J)
A, B, C, D: 2 - 218 (UniProt: P28161)

PDB	External Database	Details
Ser 210	Thr 209	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	103050.5
Non-Polymers*	Number of molecules	4
	Total formula weight	1709.9
All*	Total formula weight	104760.4

*Water molecules are not included.