2BAL

p38alpha MAP kinase bound to pyrazoloamine

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	Mitogen-activated protein kinase 14	polymer	365	42072.9	1	UniProt (Q16539) Pfam (PF00069) In PDB	Homo sapiens (human)	MAP kinase p38 alpha
2	A	[5-AMINO-1-(4-FLUOROPHENYL)-1H-PYRAZOL-4-YL][3-(PIPERIDIN-4-YLOXY)PHENYL]METHANONE	non-polymer		380.4	1	Chemie (PQA)
3		water	water		18.0	89	Chemie (HOH)

Sequence modifications

A: 2 - 360 (UniProt: Q16539)

PDB	External Database	Details
His -4	-	EXPRESSION TAG
His -3	-	EXPRESSION TAG
His -2	-	EXPRESSION TAG
His -1	-	EXPRESSION TAG
His 0	-	EXPRESSION TAG
His 1	-	EXPRESSION TAG
Css 162	Cys 161	MODIFIED RESIDUE

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	42072.9
Non-Polymers*	Number of molecules	1
	Total formula weight	380.4
All*	Total formula weight	42453.4

*Water molecules are not included.