2AZT
Crystal structure of H176N mutant of human Glycine N-Methyltransferase
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B | Glycine N-methyltransferase | polymer | 295 | 32760.2 | 2 | UniProt (Q14749) Pfam (PF13649) In PDB | Homo sapiens (human) | |
| 2 | A, B | BETA-MERCAPTOETHANOL | non-polymer | 78.1 | 5 | Chemie (BME) | |||
| 3 | A, B | CITRIC ACID | non-polymer | 192.1 | 2 | Chemie (CIT) | |||
| 4 | B | CHLORIDE ION | non-polymer | 35.5 | 1 | Chemie (CL) | |||
| 5 | water | water | 18.0 | 40 | Chemie (HOH) |
Sequence modifications
A, B: 0 - 294 (UniProt: Q14749)
| PDB | External Database | Details |
|---|---|---|
| Asn 176 | His 176 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 65520.4 | |
| Non-Polymers* | Number of molecules | 8 |
| Total formula weight | 810.4 | |
| All* | Total formula weight | 66330.8 |
