2AXI

HDM2 in complex with a beta-hairpin

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	Ubiquitin-protein ligase E3 Mdm2	polymer	115	13364.2	1	UniProt (Q9UMT8) Pfam (PF02201) UniProt (by SIFTS) (Q00987) In PDB	Homo sapiens (human)	p53-binding protein Mdm2, Oncoprotein Mdm2, Double minute 2 protein, Hdm2
2	B	cyclic 8-mer peptide	polymer	10	1399.9	1	BIRD (PRD_000326)
3	A	SULFATE ION	non-polymer		96.1	2	Chemie (SO4)
4	A	3[N-MORPHOLINO]PROPANE SULFONIC ACID	non-polymer		209.3	1	Chemie (MPO)
5		water	water		18.0	96	Chemie (HOH)

Sequence modifications

A: 17 - 125 (UniProt: Q9UMT8)

PDB	External Database	Details
His 126	-	expression tag
His 127	-	expression tag
His 128	-	expression tag
His 129	-	expression tag
His 130	-	expression tag
His 131	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	14764.2
Non-Polymers*	Number of molecules	3
	Total formula weight	401.4
All*	Total formula weight	15165.5

*Water molecules are not included.