2AL5
Crystal structure of the GluR2 ligand binding core (S1S2J) in complex with fluoro-willardiine and aniracetam
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B | Glutamate receptor 2 | polymer | 263 | 29221.7 | 2 | UniProt (P19491) Pfam (PF10613) Pfam (PF00060) Pfam (PF00497) In PDB | Rattus norvegicus (Norway rat) | GluR-2, GluR-B, GluR-K2, Glutamate receptor ionotropic, AMPA 2 |
2 | A, B | 2-AMINO-3-(5-FLUORO-2,4-DIOXO-3,4-DIHYDRO-2H-PYRIMIDIN-1-YL)-PROPIONIC ACID | non-polymer | 217.2 | 2 | Chemie (FWD) | |||
3 | A | 1-(4-METHOXYBENZOYL)-2-PYRROLIDINONE | non-polymer | 219.2 | 1 | Chemie (4MP) | |||
4 | water | water | 18.0 | 711 | Chemie (HOH) |
Sequence modifications
A, B: 3 - 117 (UniProt: P19491)
A, B: 120 - 263 (UniProt: P19491)
PDB | External Database | Details |
---|---|---|
Gly 1 | - | cloning artifact |
Ala 2 | - | cloning artifact |
PDB | External Database | Details |
---|---|---|
Gly 118 | - | SEE REMARK 999 |
Thr 119 | - | SEE REMARK 999 |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 58443.4 | |
Non-Polymers* | Number of molecules | 3 |
Total formula weight | 653.5 | |
All* | Total formula weight | 59096.9 |