1Z6F
Crystal structure of penicillin-binding protein 5 from E. coli in complex with a boronic acid inhibitor
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Penicillin-binding protein 5 | polymer | 363 | 39841.1 | 1 | UniProt (P04287) Pfam (PF00768) Pfam (PF07943) UniProt (by SIFTS) (P0AEB2) In PDB | Escherichia coli | D-alanyl-D-alanine carboxypeptidase fraction A, DD-peptidase, DD-carboxypeptidase, PBP-5 |
| 2 | A | N1-[(1R)-1-(DIHYDROXYBORYL)ETHYL]-N2-[(TERT-BUTOXYCARBONYL)-D-GAMMA-GLUTAMYL]-N6-[(BENZYLOXY)CARBONYL-L-LYSINAMIDE | non-polymer | 580.4 | 1 | Chemie (BO9) | |||
| 3 | A | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) | |||
| 4 | water | water | 18.0 | 351 | Chemie (HOH) |
Sequence modifications
A: 1 - 357 (UniProt: P04287)
| PDB | External Database | Details |
|---|---|---|
| Gly 358 | - | SEE REMARK 999 |
| Asp 359 | - | SEE REMARK 999 |
| Pro 360 | - | SEE REMARK 999 |
| Val 361 | - | SEE REMARK 999 |
| Ile 362 | - | SEE REMARK 999 |
| Asp 363 | - | SEE REMARK 999 |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 39841.1 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 672.5 | |
| All* | Total formula weight | 40513.6 |
