1YPL
X-ray crystal structure of thrombin inhibited by synthetic cyanopeptide analogue RA-1008
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | L | thrombin light chain | polymer | 27 | 3188.6 | 1 | UniProt (P00734) Pfam (PF09396) In PDB | Homo sapiens (human) | Coagulation factor II |
2 | H | Thrombin heavy chain | polymer | 257 | 29594.1 | 1 | UniProt (P00734) Pfam (PF00089) In PDB | Homo sapiens (human) | Coagulation factor II |
3 | I | Hirudin | polymer | 10 | 1363.4 | 1 | UniProt (P28504) UniProt (by SIFTS) (P01050) In PDB | Hirudo medicinalis | |
4 | H | SODIUM ION | non-polymer | 23.0 | 2 | Chemie (NA) | |||
5 | H | N-(BENZYLSULFONYL)-L-LEUCYL-N-(4-{[AMINO(IMINO)METHYL]AMINO}BUTYL)-L-PROLINAMIDE | non-polymer | 494.7 | 1 | Chemie (RA8) | |||
6 | H | GLYCEROL | non-polymer | 92.1 | 2 | Chemie (GOL) | |||
7 | water | water | 18.0 | 191 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 3 |
Total formula weight | 34146.1 | |
Non-Polymers* | Number of molecules | 5 |
Total formula weight | 724.8 | |
All* | Total formula weight | 34870.9 |