1Y6M
Crystal structure of Epstein-Barr virus IL-10 complexed with the soluble IL-10R1 chain
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | L | Viral interleukin-10 homolog | polymer | 145 | 17162.7 | 1 | UniProt (P03180) Pfam (PF00726) In PDB | Human herpesvirus 4 (Epstein-Barr virus) | vIL-10, BCRF1 protein, 20 kDa protein |
| 2 | R | Interleukin-10 receptor alpha chain | polymer | 214 | 24506.6 | 1 | UniProt (Q13651) Pfam (PF01108) In PDB | Homo sapiens (human) | IL-10R-A, IL-10R1 |
| 3 | water | water | 18.0 | 14 | Chemie (HOH) |
Sequence modifications
R: 1 - 214 (UniProt: Q13651)
| PDB | External Database | Details |
|---|---|---|
| Gln 29 | Asn 50 | engineered mutation |
| Gln 53 | Asn 74 | engineered mutation |
| Gln 89 | Asn 110 | engineered mutation |
| Gln 133 | Asn 154 | engineered mutation |
| Gln 156 | Asn 177 | engineered mutation |
| Gln 168 | Asn 189 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 41669.3 | |
| All* | Total formula weight | 41669.3 |
