1XWD
Crystal Structure of Human Follicle Stimulating Hormone Complexed with its Receptor
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, D | Glycoprotein hormones alpha chain | polymer | 92 | 10217.8 | 2 | UniProt (P01215) Pfam (PF00236) In PDB | Homo sapiens (human) | Follitropin alpha chain, Follicle-stimulating hormone alpha chain, FSH-alpha, Lutropin alpha chain, Luteinizing hormone alpha chain, LSH-alpha, Thyrotropin alpha chain, Thyroid-stimulating hormone alpha chain, TSH-alpha, Choriogonadotropin alpha chain, Chorionic gonadotrophin alpha subunit, CG-alpha |
| 2 | B, E | Follitropin beta chain | polymer | 111 | 12500.2 | 2 | UniProt (P01225) Pfam (PF00007) In PDB | Homo sapiens (human) | Follicle-stimulating hormone beta subunit, FSH-beta, FSH-B |
| 3 | C, F | Follicle stimulating hormone receptor | polymer | 252 | 28635.8 | 2 | UniProt (P23945) Pfam (PF01462) Pfam (PF13306) In PDB | Homo sapiens (human) | FSH-R, Follitropin receptor |
| 4 | G | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 1 | In PDB GlyTouCan (G42666HT) | |||
| 5 | H | beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 586.5 | 1 | In PDB GlyTouCan (G15407YE) | |||
| 6 | A, B, D, E | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 6 | Chemie (NAG) | |||
| 7 | B, C | SULFATE ION | non-polymer | 96.1 | 3 | Chemie (SO4) | |||
| 8 | water | water | 18.0 | 50 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 102707.6 | |
| Branched | Number of molecules | 2 |
| Total formula weight | 1010.9 | |
| Non-Polymers* | Number of molecules | 9 |
| Total formula weight | 1615.4 | |
| All* | Total formula weight | 105334.0 |
