1XH0
Structure of the N298S variant of human pancreatic alpha-amylase complexed with acarbose
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Alpha-amylase, pancreatic | polymer | 496 | 55904.3 | 1 | UniProt (P04746) Pfam (PF00128) Pfam (PF02806) In PDB | Homo sapiens (human) | 1,4-alpha-D-glucan glucanohydrolase, Pancreatic alpha-amylase, PA |
| 2 | A | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 1 | Chemie (NAG) | |||
| 3 | A | ACARBOSE DERIVED HEXASACCHARIDE | non-polymer | 969.9 | 1 | Chemie (AAO) | |||
| 4 | water | water | 18.0 | 280 | Chemie (HOH) |
Sequence modifications
A: 1 - 496 (UniProt: P04746)
| PDB | External Database | Details |
|---|---|---|
| Ser 298 | Asn 313 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 55904.3 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 1191.1 | |
| All* | Total formula weight | 57095.4 |
